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Author

Hyun Yang

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Open access Sep 2026

PNPLA3 Is Associated With Hepatocellular Carcinoma, While a Five-Variant Polygenic Risk Score Shows Limited Discrimination in Korean Patients With MASLD.

BACKGROUND/AIMS Genetic variants in PNPLA3, TM6SF2, MBOAT7, GCKR, and HSD17B13 have been associated with MASLD progression and hepatocellular carcinoma (HCC). We evaluated their associations with prevalent HCC and the performance of a five-variant polygenic risk score (PRS-5) in Korean patients with MASLD. METHODS A...

Jaejun Lee, J. Cha, Hee Sun Cho et al. · 0 citations
Open access Sep 2026

Dose–response relationship between tea consumption and mortality, cardiovascular, cerebrovascular, and renal outcomes in metabolic dysfunction-associated steatotic liver disease: a prospective cohort study

Tea is a widely consumed plant-derived beverage with potential metabolic and vascular effects, but its prognostic dose–response relationship in metabolic dysfunction-associated steatotic liver disease (MASLD) remains unclear. We analyzed 360,548 UK Biobank participants, including 169,241 individuals with MAS...

Tom Ryu, Jaejun Lee, Ji Won Han et al. · 0 citations

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