Malformin A1 Enhances 5-Fluorouracil-induced Apoptosis, Cell Cycle Arrest, and Anti-angiogenesis in Colorectal Cancer Cells
Background/Aim: Malformin A1 (MA1), a fungal-derived cyclic pentapeptide, has been reported to exhibit anti-cancer activity. 5-fluorouracil (5-FU) is a widely used chemotherapeutic agent that inhibits DNA and RNA synthesis and suppresses colorectal cancer (CRC) cell growth. This study aimed to investigate whether MA1 e...