Tumor hypoxia is a pervasive feature of solid tumors that promotes malignant progression, metastatic dissemination, and resistance to chemotherapy, radiotherapy, and immunotherapy. At the same time, low oxygen tension creates a chemically exploitable vulnerability for selective drug activation. Hypoxia-activated prodru...
Sanu Karan, Hyunseung Lee, Jong Seung Kim et al.· Pharmaceutics· 0 citations
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