Open access
Aug 2026
Transcriptional landscape of direct reprogramming toward the hematopoietic lineage
Summary Direct reprogramming of human fibroblasts into hematopoietic stem cells (HSCs) offers a promising strategy for generating autologous cells to treat blood and immune disorders. Current protocols are limited by low efficiency and insufficient tools for evaluating reprogramming outcomes. Although functional assays...
Jillian Cwycyshyn, Cooper M. Stansbury, S. Golts et al.
· iScience · 0 citations