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Open access Oct 2026

Too early for LATE? Age at onset is associated with the clinical and neuroimaging expression of limbic-predominant age-related TDP-43 pathology in Alzheimer's disease

Limbic-predominant age-related TDP-43 encephalopathy neuropathologic change (LATE-NC) frequently co-occurs with Alzheimer's disease (AD) pathology and has been studied mainly in older populations. We examined its frequency and expression in 196 individuals with autopsy-confirmed intermediate-to-high AD neuropathologic...

N. Zhu, R. LaJoie, I. Allen et al. · 0 citations

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