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I. Bernardini

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Open access Oct 2026

The impact of PROgnostic SIgnatures in stage II colon cancer patients enrolled in the phase III clinical trial TOSCA: the PROSIT study.

BACKGROUND Adjuvant chemotherapy (ACT) indication in stage II colorectal cancer (CRC) remains challenging, as clinical, pathological, and ctDNA inadequately predict benefit. Immune infiltration correlates with outcome, yet transcriptional signatures have not been systematically evaluated in prospective trial cohorts. W...

A. Puccini, Lorenzo Ferrando, G. Frige' et al. · 0 citations
Oct 2026

The Right to Choose at the End of Life: Opinions, Experiences, and Perceptions of the Italian Population Regarding Euthanasia. An Observational Study.

INTRODUCTION Euthanasia has long been at the center of extensive debate at the social, political, legal, and religious levels, assuming an increasingly significant role within the contemporary end-of-life context. To analyze the attitudes of the Italian population toward euthanasia using the Euthanasia Attitude Scale (...

E. Vitale, Ivan Rubbi, Federico Cucci et al. · 0 citations

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