Detection of Polysaccharide Markers of Fungal Infections by Surface-Enhanced Raman Scattering and Machine Learning Methods
In this study, we used the SERS method for the first time to measure the spectra of four polysaccharide markers of fungal infections: linear β-(1→3)- and β-(1→6)-linked D-glucans, branched mannan of Candida albicans and galactomannan of Aspergillus fumigatus. Aqueous solutions of the polysaccharides were studied in con...