Imatinib Mesylate and Sirolimus Inhibit Vascular Fibroproliferative Remodeling in Pulmonary Vein Stenosis
Highlights What are the main findings? In three patients with pulmonary vein stenosis (PVS), fibroproliferative remodeling was observed in pulmonary veins resected during surgical anatomical repair, which exhibited increased wall shear stress (WSS). The cellular substrate underlying this process appeared to be driven b...