Blood–brain barrier (BBB) dysfunction is implicated as a key link between neuroinflammation and neurodegeneration in Alzheimer’s disease (AD). Peripheral inflammation may exacerbate cognitive decline by promoting BBB breakdown and impairing clearance of amyloid and tau, yet in vivo evidence for this hypothesis remain...
B. McCausland, A. Varatharaj, N. Huneke et al.· Scientific Reports· 0 citations
Lipid traits are established risk factors for atherosclerotic disease; however, their relationship with intracranial aneurysms and subarachnoid haemorrhage (SAH) remains unclear. Recent Mendelian randomisation (MR) studies have reported inconsistent findings. This study aimed to review the literature and assess the ass...
F. Ewbank, C. Pinn, Benjamin Gaastra et al.· Translational Stroke Researc...· 0 citations
Multiple sclerosis (MS) is a chronic neurological disease whose diagnosis typically relies on resource-intensive and partly invasive procedures such as MRI and spinal fluid analysis. This study explores whether deep learning can identify distinguishing patterns in RBC images associated with MS, aiming to determine whet...
Dylan Tijburg, Noor Christoph, Tahir Nawaz et al.· Journal of Imaging· 0 citations
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