Author

I. M. Calassa

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Open access 2026

Reclassification of variants of uncertain significance in genes associated with hereditary breast cancer in patients treated at referral hospitals in the state of Goiás

Introduction: Breast cancer is the most common malignancy among women, with 5–10% of cases arising from hereditary predisposition, driven by pathogenic variants in DNA repair genes such as BRCA1/BRCA2, as well as moderate-risk genes, including ATM, CHEK2, TP53, BARD1, and BRIP1. Next-generation sequencing improves vari...

Bruno Eduardo Feitosa Nascimento, I. M. Calassa, Luiz Henrique Alves Costa et al. · Mastology · 0 citations

Open access 2026

Recent increase in breast cancer mortality rates among young women in Brazil

Breast cancer is the leading cause of cancer-related death among women in Brazil. Understanding the regional and temporal trends in mortality from this disease, particularly in recent years and among young women aged 20–49 years, is essential for identifying inequities in healthcare access and supporting public policie...

Luiz Henrique Alves Costa, Hellen Rocha da Luz, I. M. Calassa et al. · Mastology · 0 citations