Open access
Aug 2026
Distinct Transcriptional Programs Controlled by NR5A1 and β-Catenin in Adrenocortical Carcinoma
Background/Objectives: Adrenocortical carcinoma (ACC) is a rare malignancy in which overexpression of steroidogenic factor-1 (SF-1/NR5A1) and aberrant activation of canonical Wnt/β-catenin signaling are important oncogenic events. However, the extent to which these regulatory axes converge or interact at the transcript...
J. C. D. Muzzi, B. Figueiredo, Jean Silva de Souza Resende et al.
· Medical Science · 0 citations