Background The LAST-long randomized trial tested a multidimensional, stroke coordinator-led, community-based intervention and found no overall functional benefit. Because most participants had mild stroke symptoms, whether older or frailer subgroups benefited was examined. Methods In this single-blinded randomized cont...
Håkon Ihle-Hansen, B. Thommessen, Sara Rise Langlo et al.· Journal of Rehabilitation Me...· 0 citations
The observed association between step count and cognitive function after stroke might be explained by consistent individual differences over time, rather than by temporary changes within an individual's typical level of physical activity or cognition.
Geske Luzum, S. Aam, H. Allore et al.· Brain Communications· 0 citations
Understanding of the genetic architecture of AD in the context of its main genetic driver is improved, and APOE-stratified insights may help understand and overcome side effects, inform clinical trial enrollment strategies, and create the scientific basis for targeted, mechanism-driven therapies in neurodegenerative di...
J. Thomassen, H. Leonard, Brittany Ulms et al.· Nature Genetics· 0 citations
Multimodal integration of cognitive, neuroimaging, and polygenic data in the MHS-RWD tool yields strong discrimination for both early diagnosis of dementia and AD differential diagnosis, which could support etiologically informed dementia decisions in real-world settings, with potential utility in primary care.
T. T. Filiz, V. Fominykh, K. Persson et al.· medRxiv· 0 citations
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