Open access
Sep 2026
Cross-Kingdom Structural Conservation and Diversification of Homeodomains Across Major Eukaryotic Lineages.
Homeodomain transcription factors share an ancient helix-turn-helix DNA-binding core yet regulate diverse developmental and reproductive programs across eukaryotes. We curated 355 nonredundant homeodomain structures spanning fungi, animals, and plants, including 118 experimental PDB entries and 237 high-confidence Alph...
Gloria Elisabeth Buarante, E. Damayanti, P. A. Kurniatin et al.
· Evolution & Development · 0 citations