Author

I. Thiele

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Preprint Oct 2026

gpuGEM: GPU-based linear optimisation of genome-scale metabolic models

Summary: Genome-scale metabolic models increasingly challenge CPU linear-programming solvers in repeated optimisation. We present gpuGEM, an open-source Python library for GPU-based optimisation using NVIDIA cuOpt, with size-adaptive settings validated against HiGHS and Gurobi. Across ten models spanning four orders of...

Farid Zare, T. Hulshof, I. Thiele et al. · 0 citations