Open access
Jul 2026
Reversing aging-like 3D genome disorganization in a Drosophila interphase model
Recent experimental evidence suggests that aging may arise from the progressive deterioration of the epigenetic landscape, while reversing the trend can result in cell and tissue rejuvenation. A mechanistic understanding of how restoration of a key component of this landscape – the 3D structure of the genome – can be a...
A. Onufriev, Jun-Kai Zhang, I. Sharakhov et al.
· bioRxiv · 0 citations