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Author

Ian A. York

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2 papers indexed here

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Open access Aug 2026

Memory B Cell Repertoire of a Repeatedly Vaccinated Individual Includes Influenza Hemagglutinin-Specific Cross-Group Binders with Affinity Beyond A(H1N1)pdm09 and A(H3N2) Seasonal Strains

Background/Objectives: Humans are primarily infected by two distinct seasonal influenza A virus (IAV) subtypes, A(H1N1)pdm09 and A(H3N2). Because IAV mutates rapidly, it continuously escapes existing protective antibodies. However, repeated exposure to these evolving strains increases the diversity of virus-specific me...

M. Mishina, C. Horn, Zachary Ende et al. · 0 citations
Open access Aug 2026

N-linked glycosylation sites with low occupancy support sustained circulation of the A(H3N2) influenza A virus in the human population

It is suggested that the temporary introduction of sites with low glycosylation allows influenza viruses to reduce the immune pressure on antigenic and receptor binding sites of hemagglutinin without significantly compromising viral virulence.

I. Alymova, Betlehem Mekonnen, Dong-Xia Wang et al. · 0 citations

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