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Author

Ian J. Fucci

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Open access Aug 2026

Robust structural, kinetic and biophysical characterization of wild-type human ACOD1, selected mutants and their interaction with citraconate

This work presents a thorough structural investigation that yielded the first ligand-bound structure of this protein family, which required the generation of artifact-free apo crystals, and developed a novel, low-consumption, robust kinetic assay.

Brent Runge, Hande Oktay, Ian J. Fucci et al. · 0 citations

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