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Author

Ian Jenkins

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Review Open access Aug 2026

Mechanistic Artificial Intelligence for Personalized Drug Therapy: Integrating Pharmacokinetics, Pharmacodynamics, Therapeutic Drug Monitoring, and Multiomic Systems Biology

Developments support a transition from concentration-guided dosing toward mechanism-informed precision pharmacotherapy that integrates drug exposure with biological response and clinical outcomes while maintaining rigorous standards for validation and regulatory acceptance.

Ian Jenkins, Krista Casazza, Waldemar Lernhardt et al. · 1 citation

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