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Ian K. Webb

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Open access Aug 2026

Proteoform-Resolved Cross-Linking Reveals Environment-Dependent Structural Effects of α-Synuclein S129 Phosphorylation.

A proteoform-by-environment model for IDP structure is established, in which phosphorylation effects are not fixed but are rewritten by the surrounding chemical environment, which distinguishes broad contact accessibility from the residue-level contacts that dominate each condition.

Ashlyn N. Dollar, Daniel W. Kelley, Ian K. Webb · 0 citations

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