Targeted protein degradation has transformed drug discovery by replacing occupancy-driven inhibition with event-driven removal of disease-causing proteins, opening previously “undruggable” targets, including transcription factors, scaffolding proteins, and intrinsically disordered regions, to therapeutic intervention....
Walaa S. Aburayan, Ibrahim A. Alradwan, Beshair A. Alsaffar et al.· Pharmaceutics· 0 citations
Next-generation nanocarrier systems for RNA vaccines are highlighted, with an emphasis on novel nanocarrier RNA vaccine delivery systems, and stability engineering approaches that currently limit global vaccine distribution are evaluated.
Mohannad M. Fallatah, Samiyah Al-Khaldi, Dimah K. Alrabiah et al.· Pharmaceutics· 0 citations
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