Ibrahim O. Alanazi

Lupeol- and Cis-Vaccenic Acid-Containing Bioactive Fraction of Mondia whitei Induces Vacuolation-Associated Cytotoxicity Through Autophagy–Lysosome Perturbation and Caspase-Dependent Apoptosis in Human Colorectal Adenocarcinoma Cells

Plant-derived natural products are essential and prominent contributors to drug discovery, especially as anticancer agents. Medicinal plants used in alternative therapy are often obscured by poor definitions of the underlying mechanisms behind their bioactivity. In this study, we investigated the cytotoxic and mechanis...