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Ignasi Toledano

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Open access Jul 2026

The genetic architecture of human programmed stop codon readthrough

This study provides comprehensive quantitative maps of the sequence determinants of human programmed readthrough and suggests that three examples of programmed readthrough are located on distinct local fitness peaks, each defined by different upstream and downstream architectures built around a shared CUAG core motif.

Ignasi Toledano, Fran Supek, Ben Lehner · 0 citations

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