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Author

Ignatius Jenie

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Open access Oct 2026

3D MERFISH reveals cell-type diversity generated by mRNA partitioning in spiralian embryogenesis

Cell type diversification during development is often attributed to differential gene transcription. Here, we show that, during Crepidula atrasolea embryogenesis, transcriptomically distinct cell types arise through differential distribution of pre-existing mRNAs. Combining immunofluorescence, live imaging, and whole-m...

Yi-Qun Wang, Tejasvi Patil, Stephanie Neal et al. · 0 citations
Open access Sep 2026

MERFISHEYES: Web-based Visualization and Sharing Platform for Single-cell and Single-molecule Spatial Transcriptomics

This work uses MERFISHEYES to enable browser-based visualization of all 158 spatial transcriptomics datasets in the Brain Image Library and demonstrate its capabilities in handling high-throughput 3D data with genome-scale imputation of gene expression and DNA accessibility.

Ignatius Jenie, Evan Mishkin, Elvis Smith et al. · 0 citations

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