Open access
Aug 2026
Melittin Reprograms Tumor-Associated Macrophages Through CD18-Mediated Immunomodulation.
Tumor-associated macrophages (TAMs), particularly the M2-like subtype, contribute to an immunosuppressive tumor microenvironment and promote tumor progression. Melittin, a natural bioactive peptide derived from bee venom, has been reported to exert anticancer and immunomodulatory effects; however, the cellular targets...
IkJoon Han, Hyunju Lee, Eun Ko et al.
· Phytotherapy Research · 0 citations