Review
Open access
Jul 2026
Comparative effects of drugs for adults with overweight or obesity: systematic review and network meta-analysis
Moderate to high certainty evidence supports discontinuation of drugs for adults with overweight or obesity because of adverse events to be highest with orforglipron, naltrexone-bupropion, liraglutide, phentermine-topiramate, CagriSema, and oral semaglutide.
Kai-Lei Nong, Qingyang Shi, Xinran Xie et al.
· British medical journal · 5 citations