Open access
Jul 2026
Myofibroblast- specific autophagy drives cyst growth in autosomal dominant polycystic kidney disease.
Findings reveal that autophagy in MFs is a previously unrecognized driver of cyst expansion and fibrosis in ADPKD and targeting MF-specific autophagy or its upstream regulators may represent a therapeutic strategy to limit cyst growth and fibrosis in ADPKD.
Abeda Jamadar, Viji Remadevi, Meekha M. Varghese et al.
· Cell communication and signa... · 0 citations