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Insani Fitrahulil Jannah

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Open access Sep 2026

Design, Molecular Docking, and ADMET Evaluation of Pyrazoline-Pyridine Derivatives as Dual-Target Ligands for Glucokinase (1V4S) and CDK5 (1UNL)

The development of dual-target ligands is an emerging strategy in medicinal chemistry to address complex diseases. This study aimed to evaluate six pyrazoline-pyridine derivatives (5A-5F) as potential dual-target ligands for Glucokinase (1V4S) and Cyclin-Dependent Kinase 5 (CDK5, 1UNL). Molecular docking was performed...

A. Liu, M. Kolobani, Baiq Ike Nursofia et al. · 0 citations

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