Mathematical Modeling of Dietary Timing- and Protein Quality-Responsive Liver Circadian Clock and its Function on Ribosome Biogenesis.
A semi-mechanistic mathematical model of peripheral clock synchronization and clock-controlled ribosome biogenesis in response to feeding/fasting cycles and rhythms in dietary essential amino acid (EAA) availability identifies dietary EAA stress and its regulatory pathways as important determinants of peripheral circad...