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Author

İrem Durmaz Şahin

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Open access Oct 2026

miR-548ah-3p suppresses ovarian cancer stemness and therapeutic resistance through network-level signaling reprogramming within a distinct alternative polyadenylation landscape

Therapeutic resistance and cellular plasticity remain major challenges in high-grade serous ovarian cancer (HGSOC), yet the RNA-mediated mechanisms sustaining stem-like states remain incompletely understood. Here, we investigated microRNA-driven signaling reprogramming and alternative polyadenylation (APA) dynamics i...

Deren Demirel Yavuz, Elif Merve Aydin, İrem Durmaz Şahin · 0 citations

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