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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Irene M. Stoutland

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Open access Aug 2026

Domain-swapped LuxR-type quorum sensing receptors reveal divergent ligand-response mechanisms among homologs

Key structural features governing ligand response are defined and unexpected mechanistic plasticity is revealed, providing a foundation for more informed design of next-generation quorum sensing modulators with enhanced specificity, potency, and predictable activity across diverse receptors.

Irene M. Stoutland, Susan Walker, H. Blackwell · 1 citation
Review Aug 2026

Structure-Based Insights into the Molecular Mechanisms of LuxR-Type Quorum Sensing Receptors.

Recent structural and mechanistic insights into LuxR-type receptor function are summarized, including interactions with small molecules, protein partners, and DNA, including interactions with small molecules, protein partners, and DNA.

Irene M. Stoutland, Mai V. Beauclaire, Mikael H. Elias et al. · 0 citations

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