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Irina Coin

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Review Open access Sep 2026

Gliomas with pleomorphic and pseudopapillary features (GPAP) are circumscribed tumors with targetable mutations, prolonged survival, and frequent tumor predisposition

Abstract DNA methylation profiling of CNS tumors led to the identification of HPAP (high‐grade glioma with pleomorphic and pseudopapillary features), a recently proposed entity with variable morphology, recurrent MAP‐kinase pathway activating events, and longer survival compared to glioblastoma. We aimed to independent...

A. Picca, Valeria Barresi, A. Trinquet et al. · 0 citations

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