Integrated chromatin accessibility and transcriptomic profiling provide insights into inflammation-associated endothelial remodeling in capillary malformations
Capillary malformation (CM) is a congenital vascular anomaly yet the regulatory mechanisms driving endothelial remodeling remain incompletely defined. Our previous data have shown that CM lesion-derived induced pluripotent stem cells (iPSCs), their induced ECs (iECs) and vascular organoids preserve vascular phenotypes....