Open access
Sep 2026
H3K27M Mutation Modulates the Antigenic Landscape in Diffuse Midline Glioma
Background/Objectives: Diffuse midline gliomas (DMGs) are among the most aggressive paediatric brain tumours, with the pathognomonic H3K27M mutation present in over 80% of cases. This mutation drives epigenetic dysregulation and transcriptional reprogramming, yet its impact on the tumour antigenic landscape remains poo...
Tima Shamekhi, B. Zeng, C. Sun et al.
· Cancers · 0 citations