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Author

Isaac Coelho de Sousa

3 papers indexed here

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Review Open access Oct 2026

MMSE versus MoCA for cognitive screening in Brazilian clinical practice: a comparative analysis

Background: Identifying cognitive decline—from mild cognitive impairment (MCI) to dementia—remains a major challenge in clinical practice. The Mini-Mental State Examination (MMSE) is the most widely used screening instrument, whereas the Montreal Cognitive Assessment (MoCA) was designed to detect subtle executive defic...

Letícia Fernandes de Freitas, Miguel Ramos de Oliveira, Isaac Coelho de Sousa et al. · 0 citations
Review Open access Oct 2026

Factors associated with poor adherence to antiepileptic treatment

Background: Epilepsy requires continuous antiepileptic treatment for adequate seizure control and reduction of morbidity and mortality. However, poor therapeutic adherence remains frequent and represents an important determinant of clinical instability, seizure recurrence, preventable hospitalizations, and an increased...

Maria Leticia Mota de Oliveira, Isaac Coelho de Sousa, Letícia Fernandes de Freitas et al. · 0 citations
Review Oct 2026

Clinical, laboratory, and imaging predictors of hemorrhagic transformation after intravenous thrombolysis in ischemic stroke

Background: Ischemic stroke is a leading cause of morbidity and mortality worldwide, with intravenous thrombolysis using alteplase representing the main reperfusion therapy. However, hemorrhagic transformation (HT) after thrombolysis is a serious complication associated with disruption of the blood–brain barrier, micro...

Letícia Fernandes de Freitas, Miguel Ramos de Oliveira, Isaac Coelho de Sousa et al. · 0 citations

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