Isabel Woo

Dual Role of Transcription Factors Msn2 and Msn4 in Lysosomal Remodeling Under Glucose Starvation in Yeast

Under stress conditions, the lysosome adapts its metabolic and autophagic processes. One way the lysosome accomplishes this is by regulating its proteome through the activation of transcription factor EB (TFEB). However, little is known about TFEB-independent lysosome adaptation. Here we show that yeast transcription f...