Author

Isabella Luiza Ralph de Oliveira

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Review Open access Oct 2026

MicroRNAs in autoimmune connective tissue diseases: Pathogenic roles, clinical implications, and therapeutic potential.

MicroRNAs (miRNAs) are key post-transcriptional regulators of gene expression involved in immune homeostasis, inflammation, fibrosis, and vascular remodeling. Their dysregulation has been increasingly implicated in the pathogenesis of autoimmune connective tissue diseases (ACTDs). Recent studies have identified numerou...

Juliana Renata da Silva Ferreira, K. Florencio, Júlia Roberta da Silva Ferreira et al. · Molecular Immunology · 0 citations

Review Open access Aug 2026

Dengue Virus Molecular Targets and Antiviral Drug Development: Advances, Challenges and Therapeutic Perspectives

This narrative review critically analyses the principal molecular targets of DENV, including structural proteins (C, prM/M and E), nonstructural proteins (NS1–NS5) and host factors, with emphasis on the development of small‐molecule antivirals and an evaluation of their progress in pre‐clinical and clinical studies.

Aryane Lucia da Silva Aguiar De Oliveira, José Arion da Silva Moura, Pedro César de Souza et al. · ChemistrySelect · 0 citations