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Author

Isuru M. Jayalath

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Open access Jul 2026

Discovery of low molecular weight protein-binding fragments from bead-displayed libraries: application to monomeric proteins

Various strategies to multimerize monomeric targets are explored, thus allowing them to be used as targets in this fragment discovery platform and a particularly effective and convenient strategy is to express a fusion of the POI with FOLDON, a 30-residue, homo-trimeric peptide.

Joel Tong, Isuru M. Jayalath, James V. Parsons et al. · 0 citations

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