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Author

Itay Amrom

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Aug 2026

5-Carboxamide-Substituted Barbituric Acids: Promising Scaffolds for Drug Development against Mycobacterium tuberculosis.

5-carboxamide-substituted barbituric acid derivatives are reported as a promising scaffold for developing new drugs against drug-resistant Mycobacterium tuberculosis and mode-of-action studies suggest that fenoxacrim inhibits undecaprenyl pyrophosphate synthase (UPPS) and dissipates the bacterial membrane potential.

Henok A. Sahile, B. Awasthi, Jonas E. Olsen et al. · 0 citations

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