Author

IV Yampolsky

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Open access Sep 2026

Integrated Cell-Based Transcriptomic and Pathway Profiling Enables Scalable Functional Screening of Bioactive Microalgal Extracts

Background: Microalgae and cyanobacteria represent a largely unexplored source of bioactive compounds, but systematic screening of extensive strain collections is limited by the cost and complexity of conventional chemical and pharmacological characterization. Here, we evaluated a scalable functional screening strategy...

Boris Sorokin, Anton A. Buzdin, D. Luppov et al. · Pharmaceuticals · 0 citations

Jul 2026

The first dipteran luciferase from Keroplatus testaceus evolved by repurposing of a storage protein.

The identification, cloning and functional characterization of the first dipteran luciferase from the fungus gnat Keroplatus testaceus are described, providing compelling evidence for a novel evolutionary origin for a luciferase from a storage protein, closing a long-standing gap in understanding the molecular mechanis...

A. Kotlobay, Vladislav V. Babenko, R. Ziganshin et al. · Journal of Molecular Biology · 0 citations