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Author

Ivan G. Costa

2 papers indexed here

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Open access Sep 2026

AtlasOT - The Fused Unbalanced Gromov-Wasserstein for Multimodal Integration of Disease Atlases

Single-cell and spatial multiomics technologies are transforming disease atlas construction, but computational integration of unpaired modalities remains challenging, as existing methods overlook two biological constraints of data with matching samples. First, cells should only be mapped across modalities within the sa...

Kai Peng, Mayra Ruiz, Barthélémy Caron et al. · 0 citations
Open access Jul 2026

Genome-wide multi-layered epigenomic profiling across human aging

Deep whole-genome bisulfite sequencing data from blood samples of 120 healthy donors revealed only limited association between age-associated epigenetic alterations in DNA methylation, chromatin accessibility, and histone modifications, arguing against a broadly coordinated remodeling of the aging epigenome.

M. Steiger, René Krüger, Mina Shaigan et al. · 0 citations

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