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Author

Ivan Mijakovic

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Open access Sep 2026

Display of Linoleic Acid Isomerase on Bacillus subtilis Spores for Bioconversion of Linoleic Acid to t10,c12-Conjugated Linoleic Acid

Conjugated linoleic acid (CLA) comprises positional and geometric isomers of linoleic acid (LA) that have attracted interest due to their reported biological activities. In particular, trans-10,cis-12-CLA (t10,c12-CLA) has been associated with distinct metabolic effects, but its selective production remains challenging...

Saranya Nallapareddy, Adriana Botes, Ivan Mijakovic et al. · 0 citations
Open access Aug 2026

Engineering of a Carbonic Anhydrase from Hydrogenimonas thermophila Through Fusion Tags and Surface Mutagenesis Enhances Solubility While Revealing Stability–Function Relationships

Protein solubility can limit enzyme performance in industrial applications. This is the case for some carbonic anhydrases (CAs), key enzymes for CO2 capture and utilization. In this study, we investigated an α-class CA from the thermophilic bacterium Hydrogenimonas thermophila (HtCA), which was predominantly expressed...

C. Manyumwa, Carsten Jers, Ivan Mijakovic · 0 citations

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