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Author

Iván Sandino-Somoza

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Oct 2026

Systemic administration of poly(I:C) and resiquimod reprograms tumor-associated macrophages and prevents tumor progression and metastasis in murine cancer models.

Tumor-associated macrophages (TAMs) drive the immunosuppressive tumor microenvironment (TME), promoting oncogenic progression, metastasis and treatment resistance. While we previously established that intratumoral administration of poly(I:C) and R848 (TLR3 and TLR7/8 agonists) has strong therapeutic efficacy and trigge...

Clément Anfray, A. Pensado-López, F. Castro et al. · 0 citations

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