Beyond Clonal Hematopoiesis: Somatic Hematopoietic Mutations as Drivers of Cardiovascular Disease and Targets for Precision Therapy
Somatic hematopoietic mutations, particularly clonal hematopoiesis of indeterminate potential (CHIP), represent an emerging link between aging, inflammation and cardiovascular disease beyond their established relevance in hematology. This narrative review examines how acquired mutations in hematopoietic stem and progen...