Author

J. Adler

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Open access Jul 2026

Distinct forms of dopamine transmission control locomotion and learning

The neuromodulator dopamine is essential for voluntary movement and learning from experience. While these behaviors often occur simultaneously and rely on overlapping nigrostriatal dopamine circuits, they are also separable and can manifest independently. How a single neuromodulatory system controls such disparate aspe...

Matthew M McGregor, Andrew G. Yee, Selin Ekici et al. · bioRxiv · 0 citations

Open access Jul 2026

Dopamine D2 receptors bypass canonical signaling to directly tune NMDA receptor function and aversive learning

It is shown that D2Rs can bypass second messenger systems to tune glutamatergic transmission through receptor-receptor interactions, providing a mechanism by which dopamine selectively gates specific glutamatergic inputs to control striatal plasticity and behavioral adaptation.

Sheng Gong, J. Adler, Ying Zhu et al. · Science Advances · 0 citations