Author

J. Ávila-Pacheco

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Open access Aug 2026

The Role of Distress-related Metabolic Dysfunction in Ovarian Cancer Development: a pooled case-control study

Background: Evidence suggests chronic distress influences ovarian cancer (OC) etiology and metabolomic profiles. Here, we evaluated the association of a metabolite-based distress score (MDS) and OC risk. Methods: We included two matched case-control studies nested within the Nurses' Health Studies (N=584) and the Prost...

N. Lin, R. Balasubramanian, Giulia Menichetti et al. · medRxiv · 0 citations

Open access May 2024

Genetic screening and metabolomics identify glial adenosine metabolism as a therapeutic target in Parkinson’s disease

Neuronal α-synucleinopathies, including Parkinson’s disease (PD) and dementia with Lewy bodies (DLB), lack disease-modifying therapies. We developed a Drosophila model for identifying novel glial-based therapeutic targets for α-synucleinopathies. In this model, human α-synuclein is expressed in neurons and individual g...

MJ Sodders, J. Ávila-Pacheco, EC Okorie et al. · bioRxiv · 1 citation