Author

J. Biegus

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Open access Jul 2026

Spironolactone in the Treatment of Heart Failure with Mildly Reduced or Preserved Ejection Fraction: Design and Baseline Characteristics of the SPIRIT-HF-DZHK08 Trial.

SPIRIT-HF addresses key evidence gaps for spironolactone in high-risk HFpEF/HFmrEF, and could inform guideline recommendations on MRA use in this cohort.

D. Zurkan, B. Pieske, J. Petutschnigg et al. · European Journal of Heart Fa... · 1 citation

Open access Sep 2026

New Evidence in Heart Failure: 2026 Update.

Therapeutic developments continue to reshape HF management across the spectrum of left ventricular ejection fraction, and support the transition from a predominantly phenotype-based approach towards a more personalized and biologically informed model of HF care.

Valentino Liguori, Angelica Rizzello, M. Adamo et al. · ESC Heart Failure · 0 citations