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Review Open access Sep 2026

Therapy-Induced Senescence in Cancer Treatment Resistance: Mechanisms, Evidence, and Translational Opportunities

Cellular senescence is a heterogeneous and context-dependent stress response that can influence cancer treatment response. Therapy-induced senescence (TIS) may initially suppress tumor growth through durable proliferative arrest, whereas persistence of senescent cells may, in specific contexts, contribute to recurrence...

J. Blanco, A. Carnero · 0 citations

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