Author

J. Bornhorst

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Open access Oct 2026

Clinical Factors Associated With Discordant Plasma P-Tau217 and Established Alzheimer Disease Biomarkers.

BACKGROUND AND OBJECTIVES Plasma phosphorylated tau (p-tau) 217 is increasingly used for Alzheimer disease (AD) diagnosis and treatment decisions but may be discordant with established AD biomarkers. False-positive (FP) plasma results may lead to overtreatment and false-negative (FN) results to missed or delayed diseas...

D. Shir, A. Algeciras-Schimnich, Y. Piura et al. · Neurology · 0 citations

Open access Aug 2026

Optimized plasma p‐tau217 and p‐tau217/Aβ42 cutoffs enhance detection of pre‐clinical Alzheimer's disease across diverse participants

Plasma p‐tau217 and p‐tau217/Aβ42 reliably identify non‐Hispanic White individuals with symptomatic and pre‐clinical AD. However, performance across ethnoracially diverse groups remains unknown.

Y. Piura, P. Aduen, Leah Schecter et al. · Alzheimer's & Dementia · 0 citations