Treatment response to daratumumab in antibody-mediated kidney allograft rejection: evidence from serial protocol biopsies
ABSTRACT Background Antibody-mediated rejection (ABMR) is a major cause of chronic allograft dysfunction and graft loss after kidney transplantation (KTx). Daratumumab, antibody targeting the transmembrane glycoprotein CD38 (cluster of differentiation) on immune cells, has shown promise in the treatment of refractory A...