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Open access Sep 2026

Ten numbers from the Laplace–Beltrami spectrum facilitate training-free classification of protein structures based on surface shape

The comparison of protein structures is necessary to determine molecular functions and evolutionary relationships and can also facilitate drug design and the prediction of separation options. The number of available protein structures is rapidly increasing, driven by experimental determination but also prediction metho...

M. Fernández-Giro, J. Emonts, B. Berkels et al. · 0 citations
Open access Aug 2026

An integrated automated pipeline for cloning, transient expression, and purification augmenting the plant cell pack platform for biopharmaceutical screening.

Biopharmaceuticals, particularly monoclonal antibodies (mAbs), are a rapidly expanding class of therapeutics and have benefitted from high-throughput screening (HTS) strategies for protein engineering. Obtaining such complex biopharmaceuticals from plants might be advantageous because transient expression can yield gra...

Monique Schulze, Patrick Opdensteinen, Sandor Albert et al. · 0 citations

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